Friday, August 16, 2013

Nanoparticles reprogram immune cells to fight cancer

Researchers at the University of Georgia are developing a new treatment technique that uses nanoparticles to reprogram immune cells so they are able to recognize and attack cancer.

“What we are working on is specifically geared toward breast cancer,” said Shanta Dhar, the study’s co-author and an assistant professor of chemistry in the UGA Franklin College of Arts and Sciences.

Effective immune stimulation

“Our paper reports for the first time that we can stimulate the immune system against breast cancer cells using mitochondria-targeted nanoparticles and light using a novel pathway.”

A new cancer vaccine

She cautions that the results are preliminary, and the approach works only with certain forms of breast cancer. But if researchers can refine the process, this technology may one day serve as the foundation for a new cancer vaccine used to both prevent and treat disease.

“We particularly hope this technique could help patients with advanced metastatic disease that has spread to other parts of the body,” said Dhar, who also is a member of the UGA Nanoscale Science and Engineering Center, Cancer Center and Center for Drug Discovery.

Source: http://www.kurzweilai.net/nanoparticles-reprogram-immune-cells-to-fight-cancer

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